Acambis PLC Becomes First Company To Enter Phase II Testing Of Vaccine Against West Nile Virus

Acambis becomes first company to enter Phase II testing of vaccine against West Nile virus Cambridge, UK and Cambridge, Massachusetts - 20 December 2005 - Acambis plc (“Acambis”) (LSE: ACM, NASDAQ: ACAM) announces that it has started a Phase II clinical trial of its investigational vaccine against the West Nile virus, ChimeriVax™-West Nile, in healthy adult subjects. Acambis is the first company to enter a Phase II trial of a West Nile vaccine.

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