The data was presented during a late-breaking session at the 29th Transcatheter Cardiovascular Therapeutics meeting.
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| [30-October-2017] |
| DENVER, Oct. 30, 2017 /PRNewswire/ -- Abbott (NYSE: ABT) today announced that patients who underwent minimally-invasive implantation with a XIENCE coronary stent for left-main coronary artery disease had the same long-lasting health outcomes at three years but felt better more quickly than patients who underwent open-heart surgery. The data were presented during a late-breaking session at the 29th Transcatheter Cardiovascular Therapeutics (TCT) meeting, the annual scientific symposium of the Cardiovascular Research Foundation. “For any treatment, it’s important to not only consider clinical outcomes such as recurrent heart attacks or stroke, but also to consider the effect of the treatment on a patient’s quality of life,” said Suzanne J. Baron, M.D., study investigator and assistant professor of medicine at the University of Missouri-Kansas City. “These data demonstrate that PCI is a reasonable treatment option for patients with left main coronary artery disease that allows them to potentially avoid surgery and to rapidly obtain a better quality of life after revascularization.” Quality-of-life was assessed at baseline, one month, one year, and three years. Patients were asked to report frequency of chest discomfort (angina), difficulty breathing, symptoms of depression and other physical and mental limitations. After one month, patients who underwent percutaneous coronary intervention with XIENCE reported significantly greater freedom from angina (72 percent vs 70 percent; p<0.01); no difficulty breathing (60 percent vs 44 percent; p<0.01); and significantly fewer symptoms of clinical depression (8 percent vs 19 percent; p<0.01) than patients who had surgery. The significantly fewer symptoms of clinical depression extended to one year for XIENCE patients versus surgery patients (8 percent vs 12 percent; p=0.03) and were comparable by year three (9 percent vs 8 percent; p=0.77). Freedom from angina and difficulty breathing were comparable after one year and maintained out to three years. Eighty-one percent of patients in the XIENCE group reported freedom from chest discomfort at three years compared with 82 percent in the surgery group (p=0.10). Forty-three percent of patients who received XIENCE vs 42 percent of surgery patients reported no difficulty in breathing at year three (p=0.77). The findings were consistent across different types of patients including people with diabetes, frequent chest pain before treatment and people over the age of 75. “For years, we’ve debated over the best way to restore vessel function to patients with coronary artery disease,” said Charles Simonton, M.D., chief medical officer of Abbott’s vascular business. “It’s important to weigh the benefits and risk of any treatment, and these data provide confidence that XIENCE can be considered as a potential option for many types of patients with coronary artery disease, including those with left-main disease.” About coronary artery disease: About the study: About XIENCE: For U.S. Important Safety Information, visit: https://vascular.abbott.com/Xience-Stent-Safety.html#isi About Abbott: Connect with us at www.abbott.com, on Facebook at www.facebook.com/Abbott and on Twitter @AbbottNews and @AbbottGlobal. __________________________________________
View original content with multimedia:http://www.prnewswire.com/news-releases/analysis-of-landmark-study-showed-patients-treated-for-left-main-coronary-artery-disease-with-xience-stent-felt-better-faster-and-had-similar-long-term-outcomes-to-open-heart-surgery-300545236.html SOURCE Abbott | ||
| Company Codes: NYSE:ABT |
