BERKELEY, Calif., Sept. 29, 2010 (GLOBE NEWSWIRE) -- XOMA Ltd. (Nasdaq:XOMA), a leader in the discovery and development of therapeutic antibodies, today announced that patient enrollment was recently completed for the company’s Phase 2a trial of XOMA 052 in patients with Type 2 diabetes. XOMA 052 is a therapeutic antibody candidate that inhibits the inflammatory cytokine interleukin-1 beta (IL-1 beta) that may be a major cause of diabetes and cardiovascular disease. The Phase 2a trial follows the completion of positive Phase 1 trials in Type 2 diabetes patients and is designed to gain additional information on XOMA 052’s anti-diabetes activity including glycosylated hemoglobin (HbA1c) levels, impact on biomarkers of cardiovascular risk, and safety. XOMA anticipates reporting top line results in early January 2011 from a planned interim analysis of the first three months of treatment in this six month trial.
