Xencor Initiates Phase I Clinical Trial with XmAb2513 in Lymphoma

MONROVIA, Calif.--(BUSINESS WIRE)--Xencor, Inc., a company developing protein and antibody therapeutics, has initiated a Phase I clinical trial with its lead product candidate XmAb™2513 in patients with Hodgkin lymphoma (HL) and Anaplastic Large Cell Lymphoma (ALCL). XmAb2513 is a humanized monoclonal antibody that targets the antigen CD30. It is engineered to contain an XmAb™ Fc domain using Xencor’s Protein Design Automation® platform technology to greatly increase its cytotoxic potency.

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