Virginia Commonwealth University researchers have found that changes in the plasma lipoprotein profile of patients with severe periodontitis – a condition characterized by chronic infection and inflammation of the gums - may contribute to these patients’ elevated risk for heart disease and stroke.The findings suggest that it may be beneficial to test periodontitis patients for changes in their plasma lipoprotein profiles, so that available medication can be taken if necessary. In the December issue of the Journal of Lipid Research, researchers found that patients with generalized aggressive periodontitis generally had elevated plasma levels of a particularly bad subclass of the low density lipoprotein (LDL) called small-dense LDL.