VANCOUVER, BC -- (MARKET WIRE) -- March 28, 2007 -- Upstream Biosciences Inc. (OTCBB: UPBS) ("Upstream" or "the Company"), an emerging leader in the field of genetic diagnostics for cancer and the prediction of drug response, announces a provisional patent filing of prostate cancer biomarkers that could be useful for determining the course of treatment for prostate cancer patients. This filing meets the Company's fourth milestone related to the recent financing announced March 5, 2007.