URBANA, Ill.--(BUSINESS WIRE)--University of Illinois at Urbana-Champaign and Sigma-Aldrich® have entered into a licensing agreement which enables Sigma-Aldrich to expand the range of a powerful class of boronic acid surrogates offered to the global chemistry community. Boronic acids are building blocks for Suzuki-Miyaura cross-couplings, one of the most widely used chemical reactions to form carbon-carbon bonds. Sigma-Aldrich plans to utilize an innovative technology developed by Professor Martin Burke of the University of Illinois at Urbana-Champaign to produce surrogates for boronic acids previously not easily accessible. The availability of these surrogates is expected to greatly enhance the syntheses of many chemically important small molecules such as pharmaceuticals and natural products.