cutting edge science for greater productivity in drug discovery
MELBOURN, England & CRAIGAVON, Northern Ireland--(BUSINESS WIRE)--A strategic alliance has been formed for the marketing and sale of a complete fluorescence lifetime (FLT) technology comprising Almac Group’s proprietary FLEXYTE® FLT reagents and assays, and TTP Labtech’s new ameon® microplate reader. Customers can now gain full access to support, and buy equipment and essential reagents all from TTP Labtech, underpinned, behind the scenes, by Almac’s manufacturing and new assay development expertise.
“Becoming the ‘go-to’ company for FLT sales is an exciting new prospect for TTP Labtech”
FLT is an attractive alternative to traditional technologies such as FRET, FP and TR-FRET (including HTRF®) offering homogeneous assay formats and easy automation. Now recognised as a cost-effective and flexible screening approach, FLT has the ability to mitigate the most common forms of compound-related assay interference for better quality hits.
Developed utilising experience in peptide and protein engineering and chemical synthesis and design, Almac’s FLEXYTE assays comprise easy to use reagent chemistries and long lifetime fluorophores to deliver an efficient and economical platform for screening and profiling. The evolving assay platform addresses many major therapeutic target classes including kinases, proteases, phosphatases, DUBs and an increasing number of epigenetic targets and protein-protein interactions (PPIs).
TTP Labtech’s ameon FLT reader technology has been optimised for Almac’s FLEXYTE assays through an extensive beta-partner program involving four major pharmaceutical companies. The result is a system providing high speed, precise measurement of FLEXYTE assays that can be readily integrated into HTS workflows.
“We are extremely excited to bring to the market a compelling and comprehensive offering for FLT equipment and assay provision. The partnership between Almac and TTP Labtech unlocks synergy and leverages great strength and depth from both organisations.” said Dr Stephen Barr, President and Managing Director of Almac’s Sciences’ Business Unit.
“Becoming the ‘go-to’ company for FLT sales is an exciting new prospect for TTP Labtech” said Dr Wayne Bowen, Chief Scientific Officer of TTP Labtech. “The FLEXYTE and ameon combination aims to set a new benchmark for productive screening through better discrimination of lead compounds”.
For further information please visit http://ttplabtech.com/applications/fluorescence-lifetime-assays/
Editors’ notes
About Almac Group
‘Partnering to Advance Human Health’
The Almac Group is an established contract development and manufacturing organisation that provides an extensive range of integrated services to over 600 companies globally within the pharmaceutical and biotech sectors. The services range from R&D, biomarker discovery and development, API manufacture, formulation development, clinical trial supply, IXRS® technology (IVRS/IWRS) through to commercial-scale manufacture.
The international company is a privately owned organisation that has organically grown over 30 years and now employs in excess of 3,500 highly skilled personnel. Almac is headquartered in Craigavon, Northern Ireland with operations across the US (Pennsylvania, North Carolina and California) and in Asia (Singapore and Tokyo).
For further information, visit www.almacgroup.com or e-mail media@almacgroup.com.
About TTP Labtech – natural innovators
TTP Labtech is an employee-owned, life science automation company that has provided high quality, robust and innovative automated laboratory equipment for pharmaceutical and biotechnology research since 2001. It offers products that minimise assay volumes and optimise workflows in its three product areas; sample management, liquid handling and cell imaging.
TTP Labtech’s main product family includes:
- nanolitre to microlitre liquid handlers which offer excellent precision and accuracy, irrespective of liquid viscosity (mosquito® Crystal, HTS, X1, HV and dragonfly®)
- acumen® and mirrorball® redefine fast cell-based imaging, delivering effortless high content screening in any environment
- high-density, robust and secure modular stores for sample management (comPOUND® at -20°C and arktic® at -80°C)
- new products in beta-testing for example, ameon® plate reader that demonstrates our experience in fluorescence lifetime (FLT)
The team of passionate, talented and dedicated individuals behind each product, and the development of collaborative relationships with our customers differentiate TTP Labtech from other technology based companies.
For further information please visit www.ttplabtech.com .
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