Collagen, Type I (collagen I), adds structure and strength to connective tissues. Mutations in the collagen I gene are associated with Ehlers Danlos syndrome, osteogenesis imperfecta and idiopathic osteoporosis. Trevigen's rat collagen I polyclonal antibodyis reactive in ELISA and can be used for Western blots and immunofluorescence in frozen and paraffin sections.
Laminin-1 is a major glycoprotein component of extracellular basement membranes, which induces a variety of cellular responses, including cell attachment. Immunofluorescence studies have revealed transient and constitutive expression of these chains, and secretion into the epithelial basement membrane. Trevigen's polyclonal mouse laminin-1 antibody can be used in the localization of laminin-1 in tissues by immunofluorescence.
Vitronectin is a plasma glycoprotein that circulates in the blood as a mixture of 75 kDa and 65 kDa forms. It is a major cell adhesive glycoprotein and is a common component of extracellular matrices and plasma. It competes effectively with other plasma proteins for binding to cells, and is often involved in cell attachment, regulation of blood coagulation and immune responses. Trevigen's Bovine vitronectin polyclonal antibody can be used in ELISAs, and for localizing vitronectin in frozen and formalin fixed, paraffin embedded tissues by immunofluorescence.
Fibronectin is an extracellular matrix protein that is found abundantly in blood, connective tissues, and provisional matrices associated with malignant transformation of migratory cells, and has demonstrated functions in both cell-cell and cell-matrix interactions. Trevigen's rabbit polyclonal antibody can be used in ELISAs, and for localizing fibronectin in frozen and formalin fixed paraffin sections by immunofluorescence.
Trevigen, Inc. develops, manufactures and markets an extensive line of Cultrex® brand products for the promotion of cell growth, cellular differentiation and for the study of cancer cell behavior. For details, contact Trevigen, at 800-873-8443, info@trevigen.com or visit our website at www.trevigen.com.
