The focus on regenerative medicine, neuro-degenerative diseases and oncology is driving the need for large-scale, high-throughput biology. High-content analysis is increasingly being used because it is particularly well-suited to complex morphological analyses of cells, cell structures such as neurites and aggregations of cells in colonies. The challenges posed by these more complex applications demand new types of imaging techniques.
Designed for more demanding high-content assays and cell biology challenges, the new Thermo Scientific ArrayScan Infinity HCS Reader features the latest in variable pin-hole confocal technology, solid-state LED illumination, live-cell and label-free capabilities, coupled with best-in- class image analysis and bioinformatics software.
The instrument’s integrated confocal module features the latest high-speed Nipkow spinning disk technology and a variable pinhole to give finer control over image acquisition across a range of objectives (magnifications), compared to traditional confocal (fixed pin-hole) technology. This offers a balance of image quality and performance that is ideal for tissues and complex morphologies such as angiogenic tubes, neurons and stem-cell colonies. The confocal module has a four-color LED Light Engine, bringing robust, laser-like performance without the complications and cost of lasers or the need for alignment of camera, confocal and laser.
The ArrayScan Infinity HCS Reader is also coupled with enhanced Thermo Scientific iDev Workflow software for multidimensional analysis. Multiple projection options for image analysis and the ability to save the stack of images to create 3D movies enable complex 3D structures to be imaged more clearly, yielding more detailed quantitative information and a deeper understanding of biological changes.
The Arrayscan Infinity HCS Reader will be demonstrated exclusively at booth #31 at the Cambridge Healthtech Institute High Content Analysis Meeting, Jan. 10-13, 2012, in San Francisco.
For more information on the entire Thermo Scientific range of products for cell analysis call 1-800- 432-4091 or visit www.thermoscientific.com/infinity.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of nearly $11 billion, we have approximately 37,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications. Visit www.thermofisher.com.
