Targeting Genes With Viruses To Select Populations Of Nerve Cells

Yale scientists have discovered a new way of illuminating MCH neurons, which may play an important role in regulating appetite and body weight, by using a virus that has been genetically engineered so that it cannot replicate. MCH neurons are located in the hypothalamus, a homeostatic regulatory center of the brain. Because these nerve cells look like any other brain cell, it has been difficult to study their cellular behavior previously.

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