Despite showing early promise in some animal studies, supplements of resveratrol, an antioxidant found aplenty in red wine, did not improve insulin sensitivity or heart health in obese men, a small trial found. Researchers found no difference in insulin sensitivity -- the measure of how well the body uses the hormone insulin -- in 24 obese but otherwise healthy men who took daily 1,500-milligram doses of resveratrol compared to other men who took an inactive placebo for four weeks.