Sirtris Pharmaceuticals: Resveratrol Studies Suggest Broad Implications for SIRT1 Activation in Neurodegenerative Eye Disorders

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging, announced today that activation of SIRT1, a member of the sirtuin family of enzymes, was shown to be neuroprotective in an animal model of optic neuritis. These findings appear in an article published in Volume 48, Number 8 of The Investigative Ophthalmology and Visual Science Journal (IOVS), Shindler et al., 2007 entitled “SIRT1 Activation Confers Neuroprotection in Experimental Optic Neuritis.”