Shrinkage of Brain Region May Signal Onset of Multiple Sclerosis, University at Buffalo Study

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Atrophy of a key brain area may become a new biomarker to predict the onset of multiple sclerosis, researchers say. If so, that would add to established criteria such as the presence of brain lesions to diagnose the progressive, incurable disorder. Using special MRI images, scientists from three continents found that the thalamus -- which acts as a “relay center” for nervous-system signals -- had atrophied in nearly 43 percent of patients who had suffered an initial neurological episode that often comes before a multiple sclerosis (MS) diagnosis.

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