Provectus Pharmaceuticals Inc. Reports Full Phase 2 Study Data on PV-10 for Metastatic Melanoma

KNOXVILLE, Tenn.--(BUSINESS WIRE)--Provectus Pharmaceuticals, Inc. (OTC BB: PVCT, http://www.pvct.com), a development-stage oncology and dermatology biopharmaceutical company, presented positive preliminary data from fully monitored study data for the entire study population of 80 subjects in its Phase 2 clinical trial of PV-10 for metastatic melanoma. An Objective Response (“OR”) was observed in 49% of subjects, with 71% of subjects achieving locoregional disease control (stable disease or better) in their injected lesions. A mean Progression Free Survival (“PFS”) of 11.7 months was observed among subjects achieving an OR. These data, along with findings on changes in visceral and nodal metastases following chemoablation of cutaneous melanoma lesions with PV-10, were included in a presentation entitled “Chemoablation of Metastatic Melanoma with PV-10,” which was delivered by Dr. Sanjiv Agarwala at the 4th Interdisciplinary Melanoma & Skin Cancer Centres Meeting, held at the Melanoma 2010 Congress in Sydney, Australia on November 4, 2010. These data were statistically equivalent to the interim Phase 2 data on the first 40 subjects, presented by Dr.
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