Protherics PLC Announces Director/PDMR Shareholding

CHESHIRE, UK--(Marketwire - July 10, 2008) - London, UK; Brentwood, TN, US: 10 July 2008 - Protherics PLC (“Protherics” or the “Company”), the international biopharmaceutical company focused on critical care and cancer, in accordance with Sections 3.1.4R of the FSA Disclosure and Transparency Rules, announces that 916,202 ordinary shares (the “Shares”) were issued to Jacques Gonella, Non-executive Director of Protherics, on 9 July 2008 following their admission to the Official List of the Financial Services Authority.

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