A protein known as cdk6 inhibits proliferation of some cell types and may play a role in the development of breast cancer, according to a report by researchers at National Jewish Medical and Research Center. Joseph Lucas, Ph.D., Erwin Gelfand, M.D., and Joanne Domenico, report in the February issue of Molecular Cancer Research, that breast-cancer cells have low to nonexistent levels of cdk6, while normal cells have relatively high levels. Cell growth in two tumor-cell lines dropped significantly when levels of cdk6 were increased inside the cells.
