Pain Therapeutics To Host Year-End Conference Call On January 17, 2006

SOUTH SAN FRANCISCO, Calif., Jan. 12 /PRNewswire-FirstCall/ -- Pain Therapeutics, Inc. , a biopharmaceutical company, today announced it will host a conference call to discuss fourth quarter and year-end 2005 financial results. The call will take place on Tuesday, January 17th at 9:30 a.m. Pacific Time/12:30 p.m. Eastern Time.

To participate in the conference call, please dial 888-396-2356 (within the U.S.) or 617-847-8709 (outside the U.S.) fifteen minutes prior to the start of the call. The call reference number is 81544426. A playback of the conference call will be available following the live event. To access the playback, please dial 888-286-8010 (within the U.S.) or 617-801-6888 (outside the U.S.) and enter reservation number 88878694.

A webcast of the conference call will also be available online at www.paintrials.com.

About Pain Therapeutics, Inc.

We are a biopharmaceutical company that develops novel drugs. We have two drug candidates, Remoxy(TM) and Oxytrex(TM), in Phase III clinical programs. Both drugs target different segments of the multi-billion dollar market to treat severe chronic pain, such as persistent low-back pain or pain due to advanced stages of osteoarthritis.

Pain Therapeutics, Inc.

CONTACT: Christi Waarich, Senior Manager of Investor Relations of PainTherapeutics, Inc., +1-650-825-3324; or media, Carney Duntsch of BurnsMcClellan, +1-212-213-0006, or cwaarich@paintrials.com, for PainTherapeutics, Inc.

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