WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)--Two-year data from a Phase IIB study of odanacatib (formerly MK-0822), an investigational, selective cathepsin-K inhibitor in development for the treatment of osteoporosis by Merck & Co., Inc., demonstrated dose-dependent increases in bone mineral density (BMD) at the total hip, lumbar spine and femoral neck fracture sites and decreased indices of bone resorption compared to placebo in postmenopausal women with low BMD. The results were reported today at the 30th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR).