NxStage Medical, Inc. Announces Conference Call Of First Quarter 2006 Results

LAWRENCE, Mass., March 22 /PRNewswire-FirstCall/ -- NxStage Medical, Inc. , announced plans to release its financial results for the first quarter ended March 31, 2006 on Tuesday, April 25, 2006 before the open of the U.S. financial markets.

NxStage will also host a conference call at 9:00 a.m. EDT on April 25, 2006 to discuss the first quarter 2006 results. To listen to the conference call, please dial (866) 831-5605 for domestic callers and (617) 213-8851 for international callers. The passcode is 45138569. A replay of the conference call will be available through May 2, 2006 by dialing 888-286-8010 (domestic) and 617-801-6888 (international), passcode 45742183. An online archive of the conference call will also be available by accessing the Investor Relations section of the company’s website at http://www.nxstage.com.

About NxStage Medical

NxStage Medical, Inc. is a medical device company, headquartered in Lawrence, Massachusetts, USA, that develops, manufactures and markets innovative systems for the treatment of end-stage renal disease, or ESRD, and acute kidney failure. For more information on NxStage and its products, please visit the company’s website at http://www.nxstage.com.

Forward-Looking Statements

This release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this release that are not clearly historical in nature are forward-looking, and the words “anticipate,” “believe,” “expect,” “estimate,” “plan,” and similar expressions are generally intended to identify forward- looking statements. The forward-looking statements in this release include NxStage’s plan to release its financial results on April 25, 2006. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors including, but not limited to, unexpected difficulty in closing the company’s financial books for the quarter and other factors that are discussed in NxStage’s Annual Report on Form 10-K for the year ended December 31, 2005 filed with the SEC. NxStage is under no obligation to (and expressly disclaims any such obligation to) update or alter its forward-looking statements, whether as a result of new information, future events or otherwise.

Contact David N. Gill Senior Vice President & Chief Financial Officer NxStage Medical, Inc. 978-687-4700

NxStage Medical, Inc.

CONTACT: David N. Gill, Senior Vice President & Chief Financial Officer ofNxStage Medical, Inc., +1-978-687-4700

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