NPS Pharmaceuticals, Inc. Release: One Year Of GATTEX(TM) Therapy Safely Reduces Parenteral Nutrition Dependence For Patients With Short Bowel Syndrome

ORLANDO, Fla.--(BUSINESS WIRE)--NPS Pharmaceuticals, Inc. (NASDAQ: NPSP) today presented positive one-year data from a Phase 3-extension study of GATTEX™ (teduglutide), an investigational product for patients dependent upon parenteral nutrition due to short bowel syndrome (SBS). SBS is primarily caused by intestinal resection and the subsequent inability to maintain oral fluid, electrolyte, and nutrient balances. The results showed GATTEX was well tolerated out to one year and provided the ability to safely reduce parenteral nutrition (PN) dependence. In addition, 75 percent of patients who responded to GATTEX during the first 24 weeks of therapy maintained their response, with many having further reductions in their PN volume. Three patients who gained independence from PN during the first 24 weeks of therapy remained off PN at week 52 and one additional patient was weaned from PN during the 28-week extension phase. These patients had so far remained PN-independent for periods ranging from 0.5 to 3.5 years.
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