Newly Discovered Gene Regulator Could Target Sickle Cell Disease, Dana-Farber Cancer Institute and Boston Children’s Cancer and Blood Disorders Center Study

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A research team from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and other institutions has discovered a new genetic target for potential therapy of sickle cell disease (SCD). The target, called an enhancer, controls a molecular switch in red blood cells called BCL11A that, in turn, regulates hemoglobin production.

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