An understanding of the interaction between hydrogen sulphide (the ‘rotten eggs’ gas) and nitric oxide, both naturally occurring in the body, could lead to the development of new therapies and interventions to treat heart failure. Research carried out by scientists from the Peninsula Medical School at the University of Exeter and the National University of Singapore has analysed the complex ‘cross talk’ between hydrogen sulphide (H2S ) and nitric oxide (NO), both gasses that occur naturally in the body, and found that the interaction may offer potential strategies in the management of heart failure.