National Institutes of Health (NIH) Researchers Find RegeneRx’s Drug Candidate Regulates Key Proteins Important In Wound Repair; Research Team Offers New Insights Into TB4’s Mechanism Of Action

BETHESDA, Md.--(BUSINESS WIRE)--Aug. 1, 2006--RegeneRx Biopharmaceuticals (AMEX:RGN) reported today that researchers at the National Institutes of Health (NIH) found that TB4, administered to wounds in laboratory animals, significantly increased several important wound healing proteins called matrix metalloproteinases (MMPs), including MMP-2 and MMP-9. The researchers surmised that it is likely that other proteinases may also be regulated (up or down) by TB4. The paper, Thymosin B4 Promotes Matrix Metalloproteinase Expression During Wound Repair, was published in the Journal of Cellular Physiology, (D. Philp, et al., 208:195:200; 2006).

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