Nanosystems Capture and Destroy Circulating Tumor Cells, University of California, Los Angeles (UCLA) Study

Physorg -- In a study published in the journal Angewandte Chemie International Edition, a team of investigators at the University of California, Los Angeles, developed a 1-by-2-centimeter silicon chip that is covered with densely packed nanopillars coated with an antibody that binds to a protein known as epithelial-cell adhesion molecule (EpCAM). EpCAM is expressed on the surface of a wide variety of solid-tumor cells but not by cells normally found circulating in the blood stream. The research team was led by Hsian-Rong Tseng, Ph.D., a member of the Nanosystems Biology Cancer Center, one of eight Centers of Cancer Nanotechnology Excellence established by the National Cancer Institute.

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