Researchers at the University of Pennsylvania have developed a method that allows gene sequencing a strand of DNA’s bases threaded through a nanoscopic hole.
In their new study, the scientists have also shown that this new technique can be applied to learn more about the structure of proteins. The new research paper was published in the journal ACS Nano.
The existing methods for this type of analysis are labor intensive. They typically involve collecting of large quantities of the protein, requiring often protein modification. These requirements are limiting these previous methods’ usefulness for understanding the behavior of the protein in its natural state.
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