Merck & Co., Inc.: ISENTRESS™ (raltegravir), in Combination with Optimized Background Therapy (OBT), Provided Sustained Viral Suppression in Highly Treatment-Experienced Patients Infected with HIV, through 48 Weeks

CHICAGO--(BUSINESS WIRE)--Results from an on-going Phase II study showed that antiretroviral suppression was sustained after 48-weeks of treatment with ISENTRESS™ (raltegravir), an investigational oral integrase inhibitor, in combination with optimized background therapy (OBT) versus placebo plus OBT in treatment-experienced HIV-infected patients failing therapy and who had virus resistant to three classes of oral antiretroviral drugs. The results from this ongoing Phase II study also showed that ISENTRESS dosed at 200 mg, 400 mg, 600 mg orally twice daily in combination with OBT was generally well tolerated in these patients (n=133).
MORE ON THIS TOPIC