Men suffering fertility problems because of a low sperm count may have flaws in the fundamental programming of their genes, known as imprinting.Nearly a quarter of men with low sperm counts showed problems with the on/off switch - or imprint - governing a crucial gene, revealed a new study of men undergoing fertility treatment. And if the control of one gene is impaired, this means others may also be defective, says Cristina Joana Marques, at the University of Porto in Portugal, and one of the research team.