Enhanced Quality Testing Addresses Guidelines for Cell Therapy and Research
Walkersville, MD (USA), 21 September 2015 – Lonza has enhanced its range of Poietics™ Human Bone Marrow-Derived Mesenchymal Stem Cells (hMSCs) by expanding the characterization of these cells to meet industry guidelines for translational and cell therapy research applications.
The newly enhanced Poietics™ Human MSCs help to ensure that researchers start their experiments with a high-quality starting population of multipotent stem cells. This robust starting population is critical for translational research and a number of other applications where stem cells can play a vital role, including gene therapy and transplantation, cell differentiation and cell-based screening assays (such as those commonly employed in drug discovery labs).
The improved hMSCs are part of a portfolio of cell culture products that form a streamlined workflow specifically optimized to deliver accurate and reliable results, encompassing Lonza’s primary adult stem cells, growth and expansion media, differentiation kits and cell-based assays.
hMSCs are highly useful cells because of their versatility. They are capable of replication as undifferentiated cells and can also differentiate into bone, cartilage, fat, muscle, tendon and marrow stroma. Lonza’s hMSCs are quality tested to differentiate into adipogenic, chondrogenic, and osteogenic lineages when cultured in the recommended differentiation medium. In accordance with the 2006 International Society for Cellular Therapy criteria, Lonza’s hMSCs are now tested to ensure the expression of CD90 and CD73, as well as confirming the absence of HLA-DR and CD19. The cells also express CD29, CD44, CD105 and CD166, and do not express CD14, CD34 or CD45.
All cells are free from mycoplasma, bacteria, yeast and fungi, and all donors and/or cell lots test negative for HIV-1, hepatitis B and hepatitis C. In addition, a certificate of analysis is provided for each cell lot purchased.
“Lonza is a leading supplier of primary and stem cell solutions for both basic and translational research. Ensuring our hMSCs meet industry guidelines is absolutely essential for the cutting-edge research our customers perform,” said Dr. Minh Hong, Marketing Manager for Stem Cells at Lonza Bioscience Solutions. The improved characterization of our hMSCs provides end-users with confidence when utilizing our cells and represents our ongoing commitment to developing the best tools for stem cell researchers.”
For more information on the newly improved hMSCs, please visit www.lonza.com/hMSC
About Lonza
Lonza is one of the world’s leading and most-trusted suppliers to the pharmaceutical, biotech and specialty ingredients markets. We harness science and technology to create products that support safer and healthier living and that enhance the overall quality of life.
Not only are we a custom manufacturer and developer, Lonza also offers services and products ranging from active pharmaceutical ingredients and stem-cell therapies to drinking water sanitizers, from the vitamin B compounds and organic personal care ingredients to agricultural products, and from industrial preservatives to microbial control solutions that combat dangerous viruses, bacteria and other pathogens.
Founded in 1897 in the Swiss Alps, Lonza today is a well-respected global company with more than 40 major manufacturing and R&D facilities and approximately 9,800 full-time employees worldwide. The company generated sales of about CHF 3.64 billion in 2014 and is organized into two market-focused segments: Pharma&Biotech and Specialty Ingredients. Further information can be found at www.lonza.com Lonza Contact Information
Lonza Cologne GmbH
Manager Marketing Communications
Petra Haberkamm
Tel +49 221 991990
Fax +49 221 99199498
marcom.lbs@lonza.com
Lonza Group Ltd
Head Corporate Communications
Dominik Werner
Tel +41 61 316 8798
Fax +41 61 316 9540
dominik.werner@lonza.com
Lonza Group Ltd
Head External Communications
Constance Ward
Tel +41 61 316 8840
Fax +41 61 316 9840
constance.ward@lonza.com
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