KOSAN Biosciences, Inc. to Present at the Future Leaders in the Biotech Industry Conference

HAYWARD, Calif., March 22 /PRNewswire-FirstCall/ -- Kosan Biosciences Incorporated announced today that Robert G. Johnson, Jr., M.D., Ph.D., Kosan’s President and CEO, will present at the Future Leaders in the Biotech Industry Conference in New York at the Millennium Broadway on Thursday, March 29, 2007 at 10:30 a.m. EST. A live webcast of the presentation can be accessed through http://www.corporate-ir.net/ireye/confLobby.zhtml?ticker=KOSN&item_id=1492729

Interested parties may also access a live webcast of the presentation by visiting the “Events Calendar” page under the “Investors/Press” tab on Kosan’s website at http://www.kosan.com. A recorded replay of the presentation will be available for two weeks.

About Kosan

Kosan Biosciences is a biotechnology company advancing two new classes of anticancer agents through clinical development -- Hsp90 (heat shock protein 90) inhibitors and epothilones. Kosan is leveraging its proprietary discovery platform to generate a pipeline of potentially significant product candidates, primarily in the area of oncology.

Hsp90 inhibitors have a novel mechanism of action targeting multiple pathways involved in cancer cell growth and survival. Kosan’s proprietary formulation of tanespimycin (KOS-953) is currently in Phase 1 and 2 clinical trials, primarily for multiple myeloma in combination with Velcade(R) and HER2-positive metastatic breast cancer in combination with Herceptin(R). In addition, intravenous and oral formulations of Kosan’s second-generation Hsp90 inhibitor, alvespimycin (KOS-1022), are being evaluated in Phase 1 clinical trials.

Epothilones inhibit cell division with a mechanism of action similar to taxanes, one of the most successful classes of antitumor agents. KOS-1584 is in Phase 1 clinical trials in patients with solid tumors. Kosan’s epothilone program is partnered with Roche through a global development and commercialization agreement.

For additional information on Kosan Biosciences, please visit the company’s website at www.kosan.com.

NOTE: Velcade(R) (bortezomib) is a registered trademark of Millennium Pharmaceuticals, Inc.

Herceptin(R) (trastuzumab) is a registered trademark of Genentech, Inc.

Kosan Biosciences Incorporated

CONTACT: Jane M. Green, VP, Corporate Communications, +1-510-731-5335, ormobile, +1-415-652-4819, or green@kosan.com

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