HIV Vaccines May Induce HIV Antibodies in Trial Participants, Can Cause False-Positive Test Result, Brigham and Women’s Hospital Study

ScienceDaily (July 22, 2010) — During trials of preventive HIV vaccines, trial participants may develop HIV-related antibody responses that could lead to a positive HIV test by routine antibody detection methods (called vaccine-induced seropositivity/reactivity [VISP]), and the potential for false-positive test results and an incorrect HIV diagnosis, according to a study in the July 21 issue of JAMA, a theme issue on HIV/AIDS.