High Throughput Single Cell Applications Set To Benefit From Dolomite’s Novel µEncapsulator 1 System

Dolomite, a world leader in microfluidics innovation, has launched the groundbreaking µEncapsulator 1 System, the only microfluidic product specifically designed to meet the needs of research biologists. This user-friendly, high throughput system offers simple, straightforward encapsulation of single cells, DNA and/or functionalised beads in high precision, identically-sized picolitre droplets.

The launch of the µEncapsulator 1 System is set to benefit scientists working on an array of applications, including characterisation of natively paired T cell receptors, isolation of monoclonal antibody coding sequences from blood samples, high throughput single cell expression profiling, droplet PCR, high sensitivity digital PCR and encapsulation in hydrogels. The µEncapsulator can individually encapsulate 300,000 cells into monodisperse droplets in 15 minutes. Samples and reagents are loaded into the 100 µl Sample Reservoir Chip for encapsulation using a 2 Reagent Droplet Chip. The microfluidic droplets produced are then collected in a temperature-controllable microcentrifuge tube for easy aliquoting into PCR tubes or cell culture multiwell plates, or imaging under a microscope. A biocompatible oil with a high dissolved gas content is used for dropletisation, enabling encapsulated live cells to be cultured for days. For ease of use, the system can be controlled using Dolomite’s advanced Flow Control Centre software, enabling a range of protocols to be performed, from simple one-click sample processing and dropletisation through to full automation.

For more information, please visit: http://www.dolomite-microfluidics.com/webshop/uencapsulator1_system

About Dolomite

Established in 2005, Dolomite Microfluidics has grown to be the world leader in the design and manufacture of high quality innovative microfluidic products.

The company offers a broad range of modular microfluidic systems, modules and components – including pumps, chips, connectors, temperature controllers, sensors, accessories and custom-made components – as well as software for analysis or automation.

Modularity, ease of use, innovation and scalability are common to all Dolomite products, which are used across a broad range of applications in biology, drug discovery, chemistry, food, cosmetics and academia.

Dolomite is a part of the Blacktrace group of companies, a world leader in Productizing Science®, and has offices in the USA, Japan, India and Brazil, as well as a worldwide network of distributors.

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