Exploring how dietary components can interact to influence the metabolic state of the body, scientists show that a high fat, low carbohydrate diet eases Alzheimer’s disease in mice. The authors of the study believe that insulin and the related hormone, insulin related growth factor-1 (IGF-1), are the key players in reducing the brain protein amyloid-beta, an indicator of Alzheimers disease."You might say that fat is the bomb, and insulin (from carbohydrate) is the fuse,” says Richard Feinman, editor of Nutrition and Metabolism, that published the study this week. The research, by Samuel Henderson at US pharma firm Accera, runs counter to previous studies suggesting a negative effect of fat on Alzheimer’s disease.
