Exelixis, Inc. Announces January 3 Webcast Discussion Of Its Co-Development Agreement With Genentech, Inc. For Small Molecule Oncology Compound

SOUTH SAN FRANCISCO, Calif., Jan. 3 /PRNewswire-FirstCall/ -- Exelixis, Inc. today announced that it has entered into an agreement with Genentech, Inc. for the worldwide co-development of XL518, a small-molecule inhibitor of MEK currently in preclinical development at Exelixis.

The discussion of the agreement by Exelixis management will be webcast today at 5:30 a.m. PT/8:30 a.m. ET and may be accessed in the Event Calendar page under Investors at www.exelixis.com .

An archive of this discussion will be available until 9:00 p.m. PT/12:00 a.m. ET on February 3, 2007. Access numbers for this replay are: 1-877-660-6853 (domestic) and 1-201-612-7415 (international); Account number is 286; Conference ID number is: 225649.

About Exelixis

Exelixis, Inc. is a development-stage biotechnology company dedicated to the discovery and development of novel small molecule therapeutics for the treatment of cancer and other serious diseases. The company is leveraging its fully integrated drug discovery platform to fuel the growth of its development pipeline, which is primarily focused on cancer. Currently, Exelixis’ broad product pipeline includes investigational compounds in Phase II and Phase I clinical development for cancer and renal disease. Exelixis has established strategic corporate alliances with major pharmaceutical and biotechnology companies, including GlaxoSmithKline, Bristol-Myers Squibb Company, Genentech, Wyeth Pharmaceuticals and Sankyo. For more information, please visit the company’s web site at www.exelixis.com .

Exelixis, Inc.

CONTACT: investors, Charles Butler, Director, Corporate Communications,+1-650-837-7277, or cbutler@exelixis.com, or media, Soleil MaxwellHarrison, Senior Manager, Corporate Communications, +1-650-837-7012, orsharrison@exelixis.com, both of Exelixis, Inc.

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