PARAMUS, N.J.--(BUSINESS WIRE)--EnzymeRx, LLC (www.enzymerx.com), a clinical-stage biotechnology company, today announced that it has launched its first clinical study of Uricase-PEG 20. Subjects have begun enrolling in a phase 1 safety, pharmacokinetic and pharmacodynamic study of single intravenous doses of Uricase-PEG 20. Last month, EnzymeRx announced that its Investigational New Drug application for intravenous Uricase-PEG 20 had become effective. EnzymeRx is pursuing the development of Uricase-PEG 20 as an intravenous agent for the management of elevated uric acid associated with tumor lysis syndrome, and as an intramuscular agent for the treatment of refractory gout.
