DURECT Corporation Invites You to Join Its Second Quarter 2007 Earnings Conference Call on the Web

CUPERTINO, Calif., July 31 /PRNewswire-FirstCall/ -- In conjunction with DURECT Corporation’s second quarter 2007 financial results press release, you are invited to listen to the conference call that will be broadcast live over the Internet on Tuesday, August 7th 2007 at 4:30 p.m. EDT.

(Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

A live audio webcast of the presentation will be available by accessing DURECT’s homepage at www.durect.com and clicking “Investor Relations.” If you are unable to participate during the live webcast, the call will be archived on DURECT’s website under Audio Archive in the “Investor Relations” section.

What: DURECT Corporation’s First Quarter 2007 Earnings Conference Call When: Tuesday, August 7th, 2007, 4:30 p.m. EDT (1:30 p.m. PDT) Where: www.durect.com and click ‘Investor Relations’ Live over the Internet - Simply log on to the Web at the address listed above.

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company developing pharmaceutical systems based on its proprietary drug delivery platform technologies. The Company currently has a number of late-stage pharmaceutical products in development addressing large markets in pain management, with a number of research programs underway targeting chronic disease and other therapeutic areas. For more information, please visit www.durect.com.

Photo: NewsCom: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGOAP Archive: http://photoarchive.ap.orgPRN Photo Desk, +1-888-776-6555 or +1-212-782-2840DURECT Corporation

CONTACT: Matthew J. Hogan, Chief Financial Officer, +1-408-777-4936, ormedia, Jeremiah Hall of Feinstein Kean Healthcare, Senior Vice President,+1-415 677-2700, jeremiah.hall@fkhealth.com

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