Drugmakers Like GlaxoSmithKline, Johnson & Johnson, And Novartis AG Break Away From Its Old Ways

For decades, drug makers have used cutting-edge science to discover medicines but have manufactured them using techniques dating to the days of the steam engine.

But now, the industry is moving toward a major upgrade. GlaxoSmithKline PLC, Johnson & Johnson and Novartis AG are among the companies building facilities to make drugs differently. Biotechs including BioMarin Pharmaceutical Inc. and Vertex Pharmaceuticals Inc. are deploying—or are about to deploy—elements of the processes in their production.

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