MEXICO CITY--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE: BMY) today announced results from a pre-specified subanalysis of the CASTLE study, in which once-daily boosted REYATAZ® (atazanavir sulfate) (REYATAZ 300 mg taken with 100 mg of ritonavir, or REYATAZ/r) and twice-daily co-formulated lopinavir 400 mg and ritonavir 100 mg (lopinavir/r), each as part of HIV combination therapy, showed similar results for undetectable viral load at 48 weeks regardless of gender in treatment-naive HIV-1 infected adults. Women comprise half of all people living with HIV around the world, and in 2006, more than 25 percent of new HIV-1 infections in the U.S. were in women.i Moreover, women have been shown to have differences in HIV viral load, drug-related side effects and drug pharmacokinetics compared to men, but there are few data to guide decision-making about choice of therapy and dosing by gende
