Beckman Coulter introduces IOTest® CD136 (RON)-PE conjugated monoclonal antibody for the identification of a receptor protein kinase potentially involved in tumor development and growth. The CD136 antigen is the product of the recepteur d’origine nantais (RON) gene. It is mainly expressed on cells of epithelial origin. The RON receptor belongs to a group of kinases that play important regulatory roles in normal tissue and can also be involved in cellular disorganization and alteration when overexpressed or mutated.
