A new study describes how bacteriophages can be enlisted to combat Proteus mirabilis, a bacterium that commonly encrusts and blocks urinary catheters.
Researchers at the University of Brighton (United Kingdom), Queen Victoria Hospital (QVH; East Grinstead, United Kingdom), and other institutions made in vitro models of the catheterized urinary tract, thus simulating a complete closed drainage system as used in clinical practice. The models were then used to mimic either an established infection or early colonization of the catheterized urinary tract, and to examine the outcomes of a single dose of a 3-phage cocktail.
