PASADENA, Calif.--(BUSINESS WIRE)--Following the exclusive license of the warfarin biomarker, 4F2, by the Marshfield Clinic to Osmetech in November 2007, the Marshfield Clinic Research Foundation, led by Michael D. Caldwell, M.D., Ph.D., has an article published in the peer-reviewed journal, Blood Online, entitled “CYP4F2 genetic variant alters required warfarin dose.” This demonstrates that the biomarker will help reduce adverse reactions to the commonly-prescribed anticoagulant used to treat and prevent thrombotic events. Because of historically high rates of adverse drug-associated events, warfarin remains under-prescribed due to variability in therapeutic dose among patients which mandates frequent monitoring.
