JCEM Publishes Data from OXiGENE-Sponsored Preclinical Study of Combretastatin A4 Phosphate / CA4P Triple-Drug Combinations in Anaplastic Thyroid Cancer

OXiGENE, Inc. (NASDAQ: OXGN, XSSE: OXGN), a clinical-stage biopharmaceutical company developing novel therapeutics to treat cancer and eye diseases, today announced the publication of data from a preclinical study of two triple-drug combinations — combretastatin A4 phosphate / CA4P, paclitaxel, and manumycin A, and CA4P, paclitaxel, and carboplatin. Both triple-drug combinations indicated positive antineoplastic activity in mouse xenograft models of anaplastic thyroid cancer (ATC) utilizing two human ATC cell lines. The study was partially funded by OXiGENE.

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