This week, in an independent experiment, Dr. Nick Loman from the University of Birmingham, looked at de novo assembly of E.coli data from a single run with approximately 10x coverage from Ion Torrent's Personal Genome Machine (PGM™). The experiment compares several commercial and open source de novo assemblers, and in this experiment CLC Genomics Workbench is not only the fastest assembler, but also has the highest N50 value.
