November 07, 2011 -- Bioworld Consulting Laboratories, LLC (BCL) announces of the start up the true human Monoclonal Antibody Production. BCL’s human monoclonal antibody technology uses a unique proprietary method to capture and immortalize natural human antibody producing cells for in vitro production of antigen specific human antibodies.
BCL has also developed a method to generate fully human monoclonal antibodies using blood from normal donors without previous exposure to the antigen. The technology uses a proprietary method to generate an antigen presentation system, which emulates the natural presentation of antigens by the immune system. The proof of concept has been tested and human monoclonal antibody producing cell lines have been established against a viral antigen and against a tumor associated antigen.
Bioworld Consulting Laboratories method for cloning natural human monoclonal antibody producing cells has several advantages:
It does not require isolation and purification of B-cells therefore no loss of antigen specific B-cells occurs, which is associated with other methods; produces natural human antibodies, which has been innately produced by the immune system; can be easily characterized and epitope mapped without recombinant technology for specific therapies; antibodies against multiple epitopes can be isolated, and combined as multiclonal or polyclonal mixture which might be more effective than a single monoclonal antibody for clinical use; once the donor blood has been obtained, it will take only 6-8 weeks to obtain the monoclonal antibody producing clones; if blood donors with previous exposure to antigen of the interest cannot be found, in vitro immunization can be done to produce human antibodies.
For more information visit www.bioworldantibodies.com
About Bioworld Consulting Laboratories:
Bioworld Consulting Laboratories is a private antibody company that was founded by in 2005. They produce the high quality antibodies and reagents to infectious agents.
