AstraZeneca PLC Release: New Sub-Analysis of PLATO ACS Study Suggests Patient Types and Stent Types Had No Impact on Findings of Reduced Rate of Stent Thrombosis With BRILINTA (ticagrelor)

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WILMINGTON, Del.--(BUSINESS WIRE)--AstraZeneca (NYSE: AZN) today announced results from a new sub-analysis of the PLATO study that evaluated the incidence of stent thrombosis in patients with acute coronary syndrome (ACS). In the PLATO study, ACS patients who were treated with percutaneous coronary intervention (PCI) and who received drug-eluting or bare metal stents demonstrated a lower risk of stent thrombosis with BRILINTA® (ticagrelor) tablets plus aspirin than with clopidogrel plus aspirin. This analysis suggests that the reduction of stent thrombosis seen with BRILINTA in the PLATO study was consistent in non–ST-elevation myocardial infarction (NSTEMI) and ST-elevation myocardial infarction (STEMI) patients, as well as stent types (bare-metal or drug-eluting stent). These data have been published in the online issue of Circulation, currently available online.

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