TARRYTOWN, N.Y.--(BUSINESS WIRE)--Regeneron Pharmaceuticals, Inc. (Nasdaq: REGN) today reported data from a preclinical study demonstrating that blocking an important cell signaling molecule, known as (Dll4), inhibited the growth of experimental tumors by interfering with their ability to produce a functional blood supply. The inhibition of tumor growth was seen in a variety of tumor types, including those that were resistant to blockade of VEGF, suggesting a novel anti-angiogenesis therapeutic approach. Study findings were published in the December 21st issue of the journal Nature. Regeneron also announced plans to develop a fully human monoclonal antibody to Dll4 that was discovered using its proprietary VelocImmune® technology.
