University of Southern California Scientist Develops New Mathematical Model to Study Disease Genetics and Evolution

USC College computational biologist Peter Calabrese has developed a new model to simulate the evolution of so-called recombination hotspots in the genome. Published March 5 in the early online edition of the Proceedings of the National Academy of Sciences, the mathematical model and its associated software bring much-needed rigor to evolutionary investigations of how natural selection acts on individual genes, said Calabrese, a research assistant professor of biological sciences.