Mixing Antidepressants And Painkillers May Be Tied To Elevated Risk Of Bleeding, Seoul National University Study

If the Food and Drug Administration warning last week wasn’t enough to make you think twice before popping that ibuprofen so liberally for every ache and pain, a paper published Tuesday should give you pause.

The population-based study, published in the BMJ, found that mixing antidepressants with common painkillers appears to be linked to a higher risk of intracranial bleeding — which occurs in the skull — shortly after starting the treatment. The researchers emphasized that their finding doesn’t necessarily mean that this drug combination causes the bleeding, but that it’s a possibility that needs to be explored further.

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