EWING, N.J.--(BUSINESS WIRE)--Antares Pharma, Inc. (AMEX:AIS) announced that its partner, Jazz Pharmaceuticals, Inc. (NASDAQ:JAZZ) plans to initiate a Phase III clinical trial for a Central Nervous System (CNS) product candidate they call JZP-7 which utilizes Antares’ ATD™ (Advanced Transdermal Delivery) system to deliver ropinirole. The product candidate is designed to provide an effective, once-daily treatment for moderate to severe restless legs syndrome (RLS). One pharmacokinetic (PK) study has been completed and data from a second PK study is being analyzed. In the first study, doses were well tolerated locally and systemically for five days. In the second study, subjects were successfully escalated to higher doses and there were no serious adverse events. Final analysis of the safety data is still ongoing. The Phase III trial is currently planned to begin in the fourth quarter of this year.
