SAN FRANCISCO--(BUSINESS WIRE)--Ambit Biosciences today announced preliminary data from a clinical trial evaluating the company’s lead compound, AC220, as an oral monotherapy treatment for patients with acute myeloid leukemia. In this ongoing, open-label, dose escalation study, durable clinical responses have been observed in patients treated with AC220. Furthermore, AC220 has been well-tolerated and is dose proportional at all doses tested. These clinical results, together with a review of the clinical pharmacokinetics and preclinical in vitro and in vivo pharmacology for AC220, were presented today at the 50th Annual Meeting of the American Society of Hematology (ASH) in San Francisco, California.
